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Article

Nucleocytoplasmic shuttling of the Cdc42p exchange factor Cdc24p.

The Journal of cell biology - 20 Mar 2000

Nern A, Arkowitz R A

Abstract excerpt

Cdc24p, the GDP/GTP exchange factor for the regulator of actin cytoskeleton Cdc42p, localizes to sites of polarized growth. Here we show that Cdc24p shuttles in and out of the yeast nucleus during vegetative growth. Far1p is necessary and sufficient for nuclear accumulation of Cdc24p, suggesting that its nuclear import occurs via an association with Far1p. Nuclear export is triggered either by entry into the cell...

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Identifiers

PMID: 10725324
DOI: 10.1083/jcb.148.6.1115
PMCID: PMC2174313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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