Article
Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.
Proceedings of the National Academy of Sciences of the United States of America - 29 Apr 1997
Park H O, Bi E, Pringle J R, Herskowitz I
Abstract excerpt
Cells of budding yeast organize their cytoskeleton in a highly polarized manner during vegetative growth. Selection of a site for polarization requires a group of proteins including a Ras-like GTPase, Bud1, and its regulators. Another group of proteins, which includes a Rho-like GTPase (Cdc42), i...
Topics
- Adaptor Proteins, Signal Transducing
- Cell Compartmentation
- Cell Cycle Proteins
- Cell Polarity
- Cytoplasm
- Fungal Proteins
- GTP Phosphohydrolases
- Guanine Nucleotide Exchange Factors
- Membranes
- Models, Biological
- Mutation
- Protein Binding
- Proto-Oncogene Proteins
- Saccharomyces cerevisiae