Article
SelTarbase, a database of human mononucleotide-microsatellite mutations and their potential impact to tumorigenesis and immunology.
Nucleic acids research - 1 Jan 2010
Woerner Stefan M, Yuan Yan P, Benner Axel, Korff Sebastian, von Knebel Doeberitz Magnus, Bork Peer
Abstract excerpt
About 15% of human colorectal cancers and, at varying degrees, other tumor entities as well as nearly all tumors related to Lynch syndrome are hallmarked by microsatellite instability (MSI) as a result of a defective mismatch repair system. The functional impact of resulting mutations depends on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
