Article
Genetic progression in sporadic endometrial and gastrointestinal cancers with high microsatellite instability
9 Jul 2002
Abstract excerpt
This study selected a series of 136 MSI-H (microsatellite instability at high frequency) gastric, colorectal, and endometrial carcinomas combining immunohistochemical analysis for hMLH1 or hMSH2 gene products and microsatellite study. The clinico-pathological profile of all tumours was correlated with the overall instability rates at coding and non-coding repeats, in order to clarify the role and the mutation...
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