Article
Increased expression of mRNA encoding ferritin heavy chain in brain structures of a rat model of absence epilepsy.
Experimental neurology - 1 Mar 2000
Lakaye B, de Borman B, Minet A, Arckens L, Vergnes M, Marescaux C, Grisar T
Abstract excerpt
Differential mRNA display was carried out to find genes that are differentially regulated in the brain of a rat strain with absence epilepsy, the genetic absence epilepsy rats from Strasbourg (GAERS). Among the 32 differentially displayed cDNA fragments actually cloned and sequenced, one shows 100% identity with the rat heavy chain ferritin (H-ferritin) mRNA. Northern blot analysis confirmed the up-regulation of...
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