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Article

Decreased gene expression of calretinin and ryanodine receptor type 1 in tottering mice.

Brain research bulletin - 15 Oct 2002

Cicale M, Ambesi-Impiombato A, Cimini V, Fiore G, Muscettola G, Abbott L C, de Bartolomeis A

Abstract excerpt

Tottering mice are a spontaneously occurring animal model of human absence epilepsy. They carry a mutation in the P/Q-type calcium channel alpha1A subunit gene which is highly expressed by cerebellar Purkinje cells. In this study, we investigated the role of calretinin and ryanodine receptor type 1 (RyR1) gene expression in the cerebellum of tottering mice. Cerebellar tissue specimens from four experimental...

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Source

Identifiers

PMID: 12372549
DOI: 10.1016/s0361-9230(02)00841-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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