Article
Phenotypic characterization of spontaneously mutated rats showing lethal dwarfism and epilepsy.
Comparative medicine - 1 Aug 2007
Suzuki Hiroetsu, Takenaka Motoo, Suzuki Katsushi
Abstract excerpt
We have characterized the phenotype of spontaneously mutated rats, found during experimental inbreeding in a closed colony of Wistar Imamichi rats. Mutant rats showed severe dwarfism, short lifespan (early postnatal lethality), and high incidence of epileptic seizures. Mutant rats showed growth retardation after 3 d of age, and at 21 d their weight was about 56% that of normal rats. Most mutant rats died without...
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