Article
Overexpression of the immediate-early genes Egr1, Egr2, and Egr3 in two strains of rodents susceptible to audiogenic seizures.
Epilepsy & behavior : E&B - 1 Jun 2017
López-López D, Gómez-Nieto R, Herrero-Turrión M J, García-Cairasco N, Sánchez-Benito D, Ludeña M D, López D E
Abstract excerpt
Genetic animal models of epilepsy are an important tool for further understanding the basic cellular mechanisms underlying epileptogenesis and for developing novel antiepileptic drugs. We conducted a comparative study of gene expression in the inferior colliculus, a nucleus that triggers audiogenic seizures, using two animal models, the Wistar audiogenic rat (WAR) and the genetic audiogenic seizure hamster...
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