Article
Epidermal overexpression of granulocyte-macrophage colony-stimulating factor induces both keratinocyte proliferation and apoptosis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Feb 2000
Breuhahn K, Mann A, Müller G, Wilhelmi A, Schirmacher P, Enk A, Blessing M
Abstract excerpt
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is released by keratinocytes in sizeable amounts only under pathological conditions, e.g., after topical application of a tumor promoter, in atopic dermatitis (AD), and after wounding. To study the biological function of this cytokine rele...
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