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Article

Inflammatory skin disease in transgenic mice that express high levels of interleukin 1 alpha in basal epidermis.

Proceedings of the National Academy of Sciences of the United States of America - 5 Dec 1995

Groves R W, Mizutani H, Kieffer J D, Kupper T S

Abstract excerpt

Resting epidermal keratinocytes contain large amounts of interleukin 1 (IL-1), but the function of this cytokine in the skin remains unclear. To further define the role of IL-1 in cutaneous biology, we have generated two lines of transgenic mice (TgIL-1.1 and TgIL-1.2) which overexpress IL-1 alph...

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Identifiers

PMID: 8524866
DOI: 10.1073/pnas.92.25.11874
PMCID: PMC40505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8524866-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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