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Article

Overexpression of IL-4 alters the homeostasis in the skin.

The Journal of investigative dermatology - 1 May 2002

Elbe-Bürger Adelheid, Egyed Alena, Olt Sabine, Klubal Radek, Mann Ulrike, Rappersberger Klemens, Rot Antal, Stingl Georg

Abstract excerpt

IL-4 has been implicated to play an important role in the pathogenesis of many inflammatory diseases including skin diseases such as atopic dermatitis. Because it is not clear which pathologic features of atopic dermatitis are dependent on IL-4, we assessed the consequences of IL-4 overexpression in the skin, using transgenic mice overexpressing IL-4 ubiquitously. Although transgenic mice display no clinical...

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Identifiers

PMID: 11982753
DOI: 10.1046/j.1523-1747.2002.01753.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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