Article
Wnt signaling influences the development of murine epidermal Langerhans cells.
The Journal of investigative dermatology - 1 Sept 2011
Becker Maria R, Choi Yeon S, Millar Sarah E, Udey Mark C
Abstract excerpt
Langerhans cells (LCs) are distinct dendritic cells (DCs) that populate stratified squamous epithelia. Despite extensive studies, our understanding of LC development is incomplete. Transforming growth factor β1 (TGFβ1) is required for LC development, but other epidermis-derived influences may also be important. Recently, EpCAM (CD326) has been identified as a cell surface protein discriminating LCs from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
