Tumours derived from HTLV-I tax transgenic mice are characterized by enhanced levels of apoptosis and oncogene expression.

doi:10.1002/(SICI)1096-9896(1998100)186:2<209::AID-PATH162>3.0.CO;2-I

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Article

Tumours derived from HTLV-I tax transgenic mice are characterized by enhanced levels of apoptosis and oncogene expression.

The Journal of pathology - 1 Oct 1998

Hall A P, Irvine J, Blyth K, Cameron E R, Onions D E, Campbell M E

Abstract excerpt

In order to investigate the role that the human T-lymphotropic virus type I (HTLV-I) tax oncogene plays in apoptosis and transformation in vivo, four lines of HTLV-I tax transgenic mice were generated under the regulatory control of the CD3-epsilon promoter-enhancer sequence. These mice develop a...

Topics

Adenoma
Animals
Apoptosis
Cell Division
Cell Transformation, Neoplastic
Gene Expression
Gene Products, tax
Genes, pX
Human T-lymphotropic virus 1
Immunoenzyme Techniques
In Situ Nick-End Labeling
Mice
Mice, Transgenic
Neoplasm Proteins
Oncogene Proteins
Phenotype
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9924438
DOI: 10.1002/(SICI)1096-9896(1998100)186:2<209::AID-PATH162>3.0.CO;2-I

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9924438-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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