Article
Lung T-helper cells expressing T-cell receptor AV2S3 associate with clinical features of pulmonary sarcoidosis.
American journal of respiratory and critical care medicine - 1 Mar 2000
Grunewald J, Berlin M, Olerup O, Eklund A
Abstract excerpt
In previous reports of studies of Scandinavian sarcoidosis patients, we have described a strong association between lung-restricted expansions of T cells expressing T-cell receptor (TCR) AV2S3 and the human leukocyte antigen (HLA)-DRB1*0301 (DR17) and -DRB3*0101 alleles, suggesting the presence of a specific antigen in sarcoidosis. In the present study, the degree of lung-accumulated TCR AV2S3(+) T cells was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
