Article
HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis.
American journal of respiratory and critical care medicine - 1 Nov 1997
Berlin M, Fogdell-Hahn A, Olerup O, Eklund A, Grunewald J
Abstract excerpt
Although most patients with sarcoidosis have a good prognosis, a significant proportion runs a more severe and prolonged disease course. There is no marker to distinguish these subpopulations of patients, however. To investigate the relationship between HLA haplotype and clinical course, 122 Scandinavian patients with sarcoidosis were genomically typed for HLA-DR, -DQA1 and -DQB1 alleles using PCR amplification...
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