Article
VEGF gene haplotypes are associated with sarcoidosis.
Chest - 1 Jan 2010
Pabst Stefan, Karpushova Anna, Diaz-Lacava Amalia, Herms Stefan, Walier Maja, Zimmer Sebastian, Cichon Sven, Nickenig Georg, Nöthen Markus M, Wienker Thomas F, Grohé Christian
Abstract excerpt
BACKGROUND: The cause of sarcoidosis is unclear. Evidence suggests that there is a genetic susceptibility toward the disease. In this study, we examined whether haplotypes of vascular endothelial growth factor (VEGF) and its receptors VEGFR-1 and VEGFR-2 are associated with the onset or the course of sarcoidosis. METHODS: Three hundred white patients with sarcoidosis and 381 matched controls were included....
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