Article
Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.
The European respiratory journal - 1 Aug 2016
Kaiser Ylva, Lepzien Rico, Kullberg Susanna, Eklund Anders, Smed-Sörensen Anna, Grunewald Johan
Abstract excerpt
Disease phenotypes of pulmonary sarcoidosis are distinguished by clinical rather than immunological criteria. We aimed to characterise patterns of CD4(+) T-cell lineage plasticity underlying the differences in clinical presentation and disease course between the acute form, Löfgren's syndrome, and the heterogeneous, potentially progressive "non-Löfgren" form.33 pulmonary sarcoidosis patients and nine controls...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
