Article
Pleiotropic effects of zebrafish protein-tyrosine phosphatase-1B on early embryonic development.
The International journal of developmental biology - 1 Nov 1999
van der Sar A M, de Fockert J, Betist M, Zivković D, den Hertog J
Abstract excerpt
Protein tyrosine phosphorylation is an important mechanism of eukaryotic cell signalling which is regulated by protein-tyrosine kinases and protein-tyrosine phosphatases. Here we report the molecular cloning of the first zebrafish protein-tyrosine phosphatase, zf-PTP-1B, the homologue of human PT...
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