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Article

The zebrafish Znt1asa17 mutant reveals roles of zinc transporter-1a in embryonic development.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) - 1 Jul 2020

Muraina Issa A, Bury Nic R, Scott Annabella, Graham Anthony, Hogstrand Christer

Abstract excerpt

BACKGROUND: Zinc is one of the vital micronutrients required through various developmental stages in animals. Zinc transporter-1 (ZnT1; Slc30a1) is essential in vertebrates for nutritional zinc uptake and cellular zinc extrusion. Knockout of ZnT1 is lethal in vertebrates and there are therefore few functional studies of this protein in vivo. METHODS: In the present study we characterised the embryonic development...

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PMID: 32199393
DOI: 10.1016/j.jtemb.2020.126496

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