Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development.

The Journal of cell biology - 24 Sept 2007

Wyatt Leila, Wadham Carol, Crocker Lesley A, Lardelli Michael, Khew-Goodall Yeesim

Abstract excerpt

Epithelial-mesenchymal transition (EMT), crucial during embryogenesis for new tissue and organ formation, is also considered to be a prerequisite to cancer metastasis. We report here that the protein tyrosine phosphatase Pez is expressed transiently in discrete locations in developing brain, hear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesoderm
Share to Oligonucleotides, Antisense
Share to Organogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Tyrosine Phosphatases, Non-Receptor

Share to Smad4 Protein

Share to Transforming Growth Factor beta1

Share to Transforming Growth Factor beta2

Share to Transforming Growth Factor beta3

Source

Open in PubMed Open full text

Identifiers

PMID: 17893246
DOI: 10.1083/jcb.200705035
PMCID: PMC2064655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17893246-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The protein tyrosine phosphatase Pez regulates TGFbeta, epithelial-mesenchymal transition, and organ development.PMID 17893246Read ↗

The role of the ZEB family of transcription factors in development and disease.Semantic proximity Read ↗

Transcriptional analysis of cleft palate in TGFβ3 mutant mice.Semantic proximity Read ↗

PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial–Mesenchymal Transition in Breast CancerSemantic proximity Read ↗

MYPT1/PP1‐Mediated EZH2 Dephosphorylation at S21 Promotes Epithelial–Mesenchymal Transition in Fibrosis through Control of Multiple Families of GenesSemantic proximity Read ↗

The WTX Tumor Suppressor Regulates Mesenchymal Progenitor Cell Fate SpecificationSemantic proximity Read ↗

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration.Semantic proximity Read ↗

Zeb1 links epithelial-mesenchymal transition and cellular senescence.Semantic proximity Read ↗

Rho-regulated myosin phosphatase establishes the level of protrusive activity required for cell movements during zebrafish gastrulation.Semantic proximity Read ↗

Piezo1 Promoted Hepatocellular Carcinoma Progression and EMT Through Activating TGF-β Signaling by Recruiting Rab5cSemantic proximity Read ↗

Wtip is required for proepicardial organ specification and cardiac left/right asymmetry in zebrafish.Semantic proximity Read ↗

TGFbeta3 inhibits E-cadherin gene expression in palate medial-edge epithelial cells through a Smad2-Smad4-LEF1 transcription complex.Semantic proximity Read ↗

Mouse prickle1, the homolog of a PCP gene, is essential for epiblast apical-basal polarity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.