Article
The association of HLA-DR alleles and T cell activation with allergic bronchopulmonary aspergillosis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1997
Chauhan B, Santiago L, Kirschmann D A, Hauptfeld V, Knutsen A P, Hutcheson P S, Woulfe S L, Slavin R G, Schwartz H J, Bellone C J
Abstract excerpt
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease caused by the mold Aspergillus fumigatus. We previously reported that the majority of T cell clones (TCC) isolated from three ABPA patients, and specific for a dominant Ag of A. fumigatus, Asp f 1, were IL-4-produci...
Topics
- Alleles
- Allergens
- Amino Acid Sequence
- Aspergillosis, Allergic Bronchopulmonary
- Aspergillus fumigatus
- Female
- Fungal Proteins
- Gene Frequency
- HLA-DR Antigens
- HLA-DR2 Antigen
- HLA-DRB1 Chains
- Histocompatibility Testing
- Humans
- Lymphocyte Activation