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Article

On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 1991

O'Sullivan D, Arrhenius T, Sidney J, Del Guercio M F, Albertson M, Wall M, Oseroff C, Southwood S, Colón S M, Gaeta F C

Abstract excerpt

We have investigated the interaction between DR1 molecules and the two antigenic peptides, tetanus toxoid 830-843 and hemagglutinin 307-319, previously known to bind most DR alleles (degenerate binding) and to be recognized by the same T cell clones in the context of different DR alleles (promiscuous T cell recognition). The DR1 affinity of these two peptides was compared with that of two other different T cell...

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PMID: 1717570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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