Article
Isolation and characterization of Leishmania mutants defective in glycosomal protein import.
Molecular and biochemical parasitology - 5 Mar 2000
Mannion-Henderson J, Flaspohler J A, Lemley K R, Rickoll W L, Parsons M
Abstract excerpt
Kinetoplastid parasites contain a unique microbody organelle called the glycosome. Several important metabolic pathways found in the cytoplasm of higher eukaryotes are compartmentalized within the glycosome in these pathogens. This fundamental difference between the host and parasite has led to consideration of the glycosome as a potential chemotherapeutic target. The genetic basis of glycosome biogenesis is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.