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Article

Glucose Transporters and Virulence in Leishmania mexicana.

mSphere - 1 Aug 2018

Feng Xiuhong, Tran Khoa D, Sanchez Marco A, Al Mezewghi Hakima, Landfear Scott M

Abstract excerpt

Glucose transporters are important for viability and infectivity of the disease-causing amastigote stages of Leishmania mexicana The Δgt1-3 null mutant, in which the 3 clustered glucose transporter genes, GT1, GT2, and GT3, have been deleted, is strongly impaired in growth inside macrophages in vitro We have now demonstrated that this null mutant is also impaired in virulence in the BALB/c murine model of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30068561
DOI: 10.1128/mSphere.00349-18
PMCID: PMC6070740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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