Article
Age of diagnosis-based linkage analysis in type 1 diabetes.
European journal of human genetics : EJHG - 1 Feb 2000
Paterson A D, Petronis A
Abstract excerpt
Genetic linkage studies of type 1 diabetes have produced a number of conflicting results, suggesting a high degree of locus heterogeneity in this disease. Approaches which model such heterogeneity will increase the power to fine map susceptibility loci. Here, using data from a genome scan of 356 affected sib pairs with type 1 diabetes, we performed heterogeneity analysis based on similarity of age at diagnosis of...
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