Article
Establishment of astrocyte cell lines from sheep genetically susceptible to scrapie.
In vitro cellular & developmental biology. Animal - 1 Jan 2000
Vilette D, Madelaine M F, Laude H
Abstract excerpt
Primary cultures of the brain from sheep embryos were used to establish cell lines after transfection by the simian virus 40 (SV40) large T gene. Two of the lines (A15 and 4A6) displayed astroglial properties. They expressed the glial fibrillary acidic protein (GFAP), intermediate filament protein vimentin, and S-100 (beta-subunit) protein. While numerous rodent and human glial cell lines are available, this is...
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