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Article

Glial cells derived from aged mouse brain in culture display both mature and immature astrocytic phenotypes.

Journal of neuroscience research - 1 Jul 1994

Vernadakis A, Kentroti S

Abstract excerpt

In earlier studies, we established glial cell cultures derived from aged (18-month-old) mouse cerebral hemispheres (MACH) and have maintained them frozen at various passages. These cultures were characterized immunocytochemically and consist of: 5% oligodendrocytes (GalC+), 75% astrocytes-type 1 (GFAP+ only), 15% astrocytes-type 2 (GFAP+ + A2B5+), and 5% progenitor glial cells (A2B5+ only). In the present study,...

Topics

Aging
Animals
Astrocytes
Brain
Cell Differentiation
Cells, Cultured
Glial Fibrillary Acidic Protein
Immunohistochemistry
Mice
Mice, Inbred C3H
Neuroglia
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vimentin

Source

Identifiers

PMID: 7932875
DOI: 10.1002/jnr.490380411

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7932875-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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