Cell culture models of transmissible spongiform encephalopathies.

Abstract excerpt

In this review, we describe the generation and use of cell culture models of transmissible spongiform encephalopathies, also known as prion diseases. These models include chronically prion-infected cell lines, as well as cultures expressing variable amounts of wild-type, mutated, or chimeric prion proteins. These cell lines have been widely used to investigate the biology of both the normal and the pathological...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blotting, Western
• Share to Electrophoresis, Polyacrylamide Gel
• Share to Enzyme-Linked Immunosorbent Assay