Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Morphological approach to assess the involvement of astrocytes in prion propagation.

Cell and tissue research - 1 Oct 2014

Hernández Rodrigo S, Sarasa Rocío, Toledano Adolfo, Badiola Juan J, Monzón Marta

Abstract excerpt

Transmissible Spongiform Encephalopathies (TSEs) are a group of neurodegenerative disorders affecting animals and humans and for which no effective treatment is available to date. Vacuolation, neuronal/neurite degeneration, deposition of pathological prion protein (PrPsc) and gliosis are changes typically found in brains from TSE affected individuals. However, the actual role of this last feature, microgliosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to GFAP gene
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurites

Share to PrPSc Proteins

Share to Purkinje Cells

Share to Scrapie

Source

Identifiers

PMID: 24931403
DOI: 10.1007/s00441-014-1928-3

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Morphological approach to assess the involvement of astrocytes in prion propagation.PMID 24931403Read ↗

The role of astrocytes in prion-like mechanisms of neurodegenerationSemantic proximity Read ↗

Neuropathology of spongiform encephalopathies in humans.Semantic proximity Read ↗

A role for astroglia in prion diseases.Semantic proximity Read ↗

Relevance of host tau in tau seeding and spreading in tauopathiesSemantic proximity Read ↗

[Transmissible spongiform encephalopathies. History, epidemiology, etiological, hyphotheses].Semantic proximity Read ↗

Non-cell autonomous astrocyte-mediated neuronal toxicity in prion diseasesSemantic proximity Read ↗

Regional pattern of microgliosis in sporadic Creutzfeldt-Jakob disease in relation to phenotypic variants and disease progression.Semantic proximity Read ↗

S100A6 overexpression within astrocytes associated with impaired axons from both ALS mouse model and human patients.Semantic proximity Read ↗

Tick-Borne Encephalitis Virus Infects Rat Astrocytes but Does Not Affect Their ViabilitySemantic proximity Read ↗

Astrocytes are key but indirect contributors to the development of the symptomatology and pathophysiology of Huntington's disease.Semantic proximity Read ↗

Phenotyping of protein-prion (PrPsc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry.Semantic proximity Read ↗

Astrocyte diversity and aging in the mouse lemur primate brainSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.