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Article

ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.

British journal of cancer - 1 Feb 2000

Ignatoski K M, Maehama T, Markwart S M, Dixon J E, Livant D L, Ethier S P

Abstract excerpt

Amplification and overexpression of ERBB-2 in human breast cancer is thought to play a significant role in the progression of the disease; however, its precise role in the aetiology of altered phenotypes associated with human breast cancer is unknown. We have previously shown that exogenous overexpression of ERBB-2 conferred growth factor independence on human mammary epithelial cells. In this study, we show that...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 10682681
DOI: 10.1054/bjoc.1999.0979
PMCID: PMC2363331

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.PMID 10682681Read ↗

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erbB-2 Overexpression in Human Mammary Epithelial Cells Confers Growth Factor Independence*Semantic proximity Read ↗

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