Article
Association between angiotensin-converting enzyme and Alzheimer disease.
Archives of neurology - 1 Feb 2000
Farrer L A, Sherbatich T, Keryanov S A, Korovaitseva G I, Rogaeva E A, Petruk S, Premkumar S, Moliaka Y, Song Y Q, Pei Y, Sato C, Selezneva N D, Voskresenskaya S, Golimbet V, Sorbi S, Duara R, Gavrilova S, St George-Hyslop P H, Rogaev E I
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme has been reported to show altered activity in patients with neurologic diseases. An insertion-deletion polymorphism in ACE has recently been linked to heart disease, cerebrovascular disease, and AD. OBJECTIVE: To determine whether the angiotensin-converting enzyme (ACE) is associated with risk of Alzheimer disease (AD). METHODS: We investigated the ACE polymorphism as a...
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