Angiotensin-converting enzyme polymorphisms AND Alzheimer's disease susceptibility: An updated meta-analysis.

doi:10.1371/journal.pone.0260498

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Article

Angiotensin-converting enzyme polymorphisms AND Alzheimer's disease susceptibility: An updated meta-analysis.

PloS one - 1 Jan 2021

Xin Xiao-Yu, Lai Ze-Hua, Ding Kai-Qi, Zeng Li-Li, Ma Jian-Fang

Abstract excerpt

BACKGROUND: Many studies among different ethnic populations suggested that angiotensin converting enzyme (ACE) gene polymorphisms were associated with susceptibility to Alzheimer's disease (AD). However, the results remained inconclusive. In the present meta-analysis, we aimed to clarify the effect of ACE polymorphisms on AD risk using all available relevant data. METHODS: Systemic literature searches were...

Topics

Alleles
Alzheimer Disease
Genetic Predisposition to Disease
Humans
Peptidyl-Dipeptidase A
Polymorphism, Genetic

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PMID: 34818351
DOI: 10.1371/journal.pone.0260498
PMCID: PMC8612529

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