Article
Interaction between apolipoprotein-E and angiotensin-converting enzyme genotype in Alzheimer's disease.
American journal of Alzheimer's disease and other dementias - 1 Jan 2000
Isbir T, Agaçhan B, Yilmaz H, Aydin M, Kara I, Eker D, Eker E
Abstract excerpt
Both apolipoprotein-E (apo-E) epsilon 4 allele and angiotensin-converting enzyme (ACE) deletion (D) polymorphism have been associated with a high risk for coronary heart disease. Increased frequency of the epsilon 4 allele has also been reported in patients with late-onset of familial and sporadic Alzheimer's disease (AD). The primary aim of this study is to examine the possible relationship between the ACE gene...
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