Article

Linkage disequilibrium between single nucleotide polymorphisms and hypermutable loci

2015-06-15

Abstract excerpt

Some diseases are caused by genetic loci with a high rate of change, and heritability in complex traits is likely to be partially caused by variation at these loci. These hypermutable elements, such as tandem repeats, change at rates that are orders of magnitude higher than the rates at which most single nucleotides mutate. However, single nucleotide polymorphisms, or SNPs, are currently the primary focus of genet...

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Literature Corpus work: e9803edc-a26c-5260-8a0e-5907a4892ccc
DOI: 10.1101/020909

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