Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimation of population parameters and recombination rates from single nucleotide polymorphisms.

Genetics - 1 Feb 2000

Nielsen R

Abstract excerpt

Some general likelihood and Bayesian methods for analyzing single nucleotide polymorphisms (SNPs) are presented. First, an efficient method for estimating demographic parameters from SNPs in linkage equilibrium is derived. The method is applied in the estimation of growth rates of a human population based on 37 SNP loci. It is demonstrated how ascertainment biases, due to biased sampling of loci, can be avoided,...

Topics

Genetic Linkage
Humans
Markov Chains
Polymorphism, Single Nucleotide
Recombination, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10655242
DOI: 10.1093/genetics/154.2.931
PMCID: PMC1460954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimation of population parameters and recombination rates from single nucleotide polymorphisms.PMID 10655242Read ↗

Recent developments in genetic data analysis: what can they tell us about human demographic history?Semantic proximity Read ↗

Methods for human demographic inference using haplotype patterns from genomewide single-nucleotide polymorphism data.Semantic proximity Read ↗

Maximum-likelihood estimation of demographic parameters using the frequency spectrum of unlinked single-nucleotide polymorphisms.Semantic proximity Read ↗

New explicit expressions for relative frequencies of single-nucleotide polymorphisms with application to statistical inference on population growth.Semantic proximity Read ↗

The discovery of single-nucleotide polymorphisms--and inferences about human demographic history.Semantic proximity Read ↗

Usefulness of single nucleotide polymorphism data for estimating population parameters.Semantic proximity Read ↗

Genealogical inference from microsatellite data.Semantic proximity Read ↗

Robust demographic inference from genomic and SNP data.Semantic proximity Read ↗

Dating rare mutations from small samples with dense marker data.Semantic proximity Read ↗

Bayesian inference of fine-scale recombination rates using population genomic data.Semantic proximity Read ↗

Genetic epidemiology of single-nucleotide polymorphisms.Semantic proximity Read ↗

Modeling linkage disequilibrium and identifying recombination hotspots using single-nucleotide polymorphism data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.