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Article

Protein-only inheritance in yeast: something to get [PSI+]-ched about.

Trends in cell biology - 1 Mar 2000

Serio T R, Lindquist S L

Abstract excerpt

Recent work suggests that two unrelated phenotypes, [PSI+] and [URE3], in the yeast Saccharomyces cerevisiae are transmitted by non-covalent changes in the physical states of their protein determinants, Sup35p and Ure2p, rather than by changes in the genes that encode these proteins. The mechanism by which alternative protein states are self-propagating is the key to understanding how proteins function as...

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PMID: 10675903
DOI: 10.1016/s0962-8924(99)01711-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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