Article
Rnq1: an epigenetic modifier of protein function in yeast.
Molecular cell - 1 Jan 2000
Sondheimer N, Lindquist S
Abstract excerpt
Two protein-based genetic elements (prions) have been identified in yeast. It is not clear whether other prions exist, nor is it understood how one might find them. We established criteria for searching protein databases for prion candidates and found several. The first examined, Rnq1, exists in distinct, heritable physical states, soluble and insoluble. The insoluble state is dominant and transmitted between...
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