Article
The protein-only theory and the yeast Saccharomyces cerevisiae: the prions and the propagons.
Cellular and molecular life sciences : CMLS - 1 Nov 2001
Fernandez-Bellot E, Cullin C
Abstract excerpt
The yeast prions represent a very attractive and tractable model for investigating the prion world. The more extensively studied yeast prion [PSI] leads to a propagation model that links auto-aggregation in amyloid formation and inactivation of the cellular function of the yeast 'prion protein' Sup35p. The other prion model, [URE3], appears to be similar in some genetic and biochemical properties. The...
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