Article
[Phenotypes of oxidation and acetylation in Alzheimer's disease--preliminary report].
Psychiatria polska - 1 Jan 2000
Milejski Piotr, Orzechowska-Juzwenko Krystyna, Niewiński Przemysław, Hurkacz Magdalena, Czarnik-Matusewicz Henryk, Leszek Jerzy, Rudzik Jacek, Grotthus Bartosz
Abstract excerpt
AIM: The relationship between genetically determined polymorphic oxidation and acetylation and susceptibility to some disease has aroused much interest. The aim of our study was to evaluate whether patients with Alzheimer's disease differ from healthy persons in their ability to oxidize sparteine and acetylate sulphadimidine as model substance. METHOD: Oxidation and acetylation phenotype were estimated in 20...
Topics
- Acetylation
- Adult
- Aged
- Alzheimer Disease
- Disease Susceptibility
- Female
- Humans
- Male
- Middle Aged
- Oxidation-Reduction
- Phenotype
- Polymorphism, Genetic
- Risk Factors
- Sparteine
- Sulfamethazine
