Article
Slow allotypic variants of the NAT2 gene and susceptibility to early-onset Parkinson's disease.
Neurology - 1 Dec 1998
Agúndez J A, Jiménez-Jiménez F J, Luengo A, Molina J A, Ortí-Pareja M, Vázquez A, Ramos F, Duarte J, Coria F, Ladero J M, Alvarez-Cermeño J C, Benítez J
Abstract excerpt
OBJECTIVE: To determine the frequency and the linkage distribution of seven mutations at the polymorphic gene coding for the arylamine N-acetyl transferase (NAT2; EC 2.3.1.5) in 121 unrelated patients with sporadic PD and in 121 unrelated healthy volunteers. METHODS: The study was performed with...
Topics
- Adult
- Age of Onset
- Aged
- Alleles
- Arylamine N-Acetyltransferase
- Female
- Gene Deletion
- Gene Expression Regulation, Enzymologic
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Mutation
- Parkinson Disease