Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The role of N-acetyltransferase polymorphism in the pathogenesis of Parkinson's disease].

Neurologia i neurochirurgia polska - 1 Jan 2000

Kłodowska-Duda Gabriela A, Opala Grzegorz M, Ochudło Stanisław G

Abstract excerpt

Pathogenesis of many diseases is related to the influence of noxious environmental agents coupled with individual genetic sensitivity that depends on the function of detoxificating enzymes. One of the latter is N-acetyltransferase 2 whose mutations lead to an impairment of the enzyme function. Genetically determined acetylation rate reduction with exposure to neurotoxins may contribute to the development of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Environmental Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Parkinson Disease

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 15174255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The role of N-acetyltransferase polymorphism in the pathogenesis of Parkinson's disease].PMID 15174255Read ↗

N-acetyltransferase 2 polymorphism in sporadic Parkinson's disease in a Polish population.Semantic proximity Read ↗

[Clinical significance of oxidation and acetylation genetic polymorphism in patients with Parkinson's disease].Semantic proximity Read ↗

Toxins, genetics, and Parkinson's disease: the role of N-acetyltransferase 2.Semantic proximity Read ↗

The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia.Semantic proximity Read ↗

Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease.Semantic proximity Read ↗

[Polymorphism of N-acetyltransferase-2 and pathogenesis of neoplastic diseases].Semantic proximity Read ↗

N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study.Semantic proximity Read ↗

Association of slow acetylator genotype of N-acetyltransferase 2 with Parkinson's disease in south Indian population.Semantic proximity Read ↗

N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease.Semantic proximity Read ↗

Association of N-acetyl transferase 2 gene polymorphism and slow acetylator phenotype with young onset and late onset Parkinson's disease among Indians.Semantic proximity Read ↗

[The molecular genetic and toxicological-ecological bases of the etiology and pathogenesis of Parkinson's diseases (parkinsonism)].Semantic proximity Read ↗

Association of polymorphism in cytochrome P450 2D6 and N-acetyltransferase-2 with Parkinson's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.