Article
N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study.
Journal of neurology, neurosurgery, and psychiatry - 1 Oct 1999
Harhangi B S, Oostra B A, Heutink P, van Duijn C M, Hofman A, Breteler M M
Abstract excerpt
The N-acetyltransferase-2 gene (NAT-2) has been associated with Parkinson's disease. The genotype associated with slow acetylation has been reported to be increased in patients with Parkinson's disease. Three mutant alleles M1, M2, and M3 of NAT-2 were investigated in 80 patients with idiopathic Parkinson's disease and 161 age matched randomly selected controls from a prospective population based cohort study....
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