Article
Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease.
Lancet (London, England) - 18 Oct 1997
Bandmann O, Vaughan J, Holmans P, Marsden C D, Wood N W
Abstract excerpt
BACKGROUND: Epidemiological studies have identified positive family history and exposure to environmental toxins as risk factors for Parkinson's disease (PD). An inherited defect of xenobiotic metabolism could result in increased susceptibility to such toxins. We investigated the frequency of functionally relevant polymorphisms in six detoxification enzymes among patients with PD to elucidate the relation between...
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