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Article

Problems and perspectives of phenotyping for drug-metabolizing enzymes in man.

International journal of clinical pharmacology and therapeutics - 1 Jan 2000

Zaigler M, Tantcheva-Poór I, Fuhr U

Abstract excerpt

Pronounced interindividual differences in drug disposition are mainly caused by differences in the activity of liver drug-metabolizing enzymes. These depend on known and unknown covariates, including genetic as well as environmental factors. Phenotyping, i.e. assessment of enzyme activities in vivo after administration of a test dose, seems to be a promising tool for determining actual metabolic capacities....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10667830
DOI: 10.5414/cpp38001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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