Article
Inherent difficulties in epidemiological studies involving phenotyping.
IARC scientific publications - 1 Jan 1999
Benhamou S, Bouchardy C, Jacqz-Aigrain E
Abstract excerpt
Phenotyping studies on a possible association between genetic polymorphisms and cancer raise specific problems that are mostly related to accurate determination of enzymatic activity in individuals. These difficulties are addressed on the basis of investigations into the relationship between the CYP2D6 phenotype and lung cancer. Only the problems concerning the design and analysis of epidemiological studies and...
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