Article
[Phenotyping of enzymes participating in drug metabolism].
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti - 1 Jun 2012
Svatopluk Světlík, Karolína Hronová, Ondřej Slanař
Abstract excerpt
Pharmacogenetics is a rapidly developing field of science promising individualization of treatment through determination of genetic polymorphism in pharmacodynamics (receptors and other drug targets) and pharmacokinetics (carriers, metabolic enzymes). Enzyme activity may be predicted using genotyping or directly phenotyped - after administration of a probe substrate. This review article deals with some important...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
