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Article

[Contribution of genotyping and phenotyping of biotransformation in therapeutic drug monitoring].

Therapie - 1 Jan 2000

Barré J

Abstract excerpt

Genetic-controlled biotransformation is a factor partly accounting for interindividual variability in drug responses. This control occurs via gene coding for polymorphic enzymes or rare genetic variants. Currently, the clinical relevance of genetically controlled biotransformation concerns only a few drugs. Determinants of clinical relevance depend on the size of the contribution of the metabolic pathway subject...

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PMID: 11475803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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