Article
Relationship between HLA-DRB1 and DQ alleles and the genetic susceptibility to type 1 diabetes.
Chinese medical journal - 1 Apr 2001
Sang Y, Yan C, Zhu C, Ni G
Abstract excerpt
OBJECTIVE: To study the relationship between human leukocyte antigen (HLA)-DRB1 and DQ alleles and the genetic susceptibility of type 1 diabetes in North Chinese children. METHODS: Polymerase chain reaction (PCR) techniques were used to amplify the second exon of DRB1 and DQ alleles, after which sequence specific olignucleotide probe (SSOP) dot blot hybridization techniques were used to analyze the amplified...
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