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Article

Constitutional genetic variation at the human aromatase gene (Cyp19) and breast cancer risk.

British journal of cancer - 1 Feb 1999

Siegelmann-Danieli N, Buetow K H

Abstract excerpt

The activity of the aromatase enzyme, which converts androgens into oestrogens and has a major role in regulating oestrogen levels in the breast, is thought to be a contributing factor in the development of breast cancer. We undertook this study to assess the role of constitutional genetic variation in the human aromatase gene (Cyp19) in the development of this disease. Our genotyping of 348 cases with breast...

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Identifiers

PMID: 10027313
DOI: 10.1038/sj.bjc.6690071
PMCID: PMC2362434

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Source receipt: pubmed, retrieved 7 Sept 2026.

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