Article
Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls.
Breast cancer research and treatment - 1 Jul 2010
Ma Xiangyu, Qi Xiaowei, Chen Chunhai, Lin Hui, Xiong Hongyan, Li Yafei, Jiang Jun
Abstract excerpt
The association of CYP19 gene polymorphisms with breast cancer has been widely reported, but results of previous studies were somewhat contradictory and underpowered. In order to overcome the limitations of individual study and to understand the real situation, we conducted a systematic review and meta-analysis including three CYP19 gene polymorphisms [R264C polymorphism, CYP19_630 3-bp del/Ins polymorphism, and...
Topics
- Aromatase
- Asian People
- Breast Neoplasms
- Case-Control Studies
- Female
- Genetic Predisposition to Disease
- Humans
- Odds Ratio
- Phenotype
- Polymorphism, Genetic
- Risk Assessment
